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KMID : 0351619690100010189
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Kyungpook Medical Journal
1969 Volume.10 No. 1 p.189 ~ p.198
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Laboratory Data in Normal Korean Mongrel Dogs
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崔璟淑/Choi, Kyung Sook
申鉉鑽/金亨洙/李在福/Shin, Hyun Chan/Lee, Jae Bok/Kim, Hyung Soo
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Abstract
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Mongrel dog is one of the commonly using experimental animal and particularly is favorable for cardio-pulmonary research study. However, control laboratory data in Korean mongrel dogs are variable with papers reported.
Present study attempted to prescribe the normal range of some laboratory data in anesthetized Korean ,mongrel dog. 25mg/kg of sodium thiopental was used as intravenous anesthetics.
Respiratory rate and minute ventilation were measured on pneumogram recorded by means of Krog´s spirometer, oxygen consumption was measured using Krog´s spirometer installed with sodalime and oxygen bag. Oxygen capacity and .saturation of arterial blood were analysed according to the methods of VanSlyke and Neill. Heart rate was counted on electrocardiogram, arterial pressure was monitored by mercury manometer and cardiac out put was measured .according to the Fick principle. Blood volume was measured by dilution method using radioac-tive chromium tagged red cells. The number of red blood cells and white blood cells were counted by means of Thoma-Zeiss hemocytometer and hematocrit was measured using microhematocrit centrifu;;e and it´s reader.
Mean value and range parenthesis) of measured laboratory data are as follows: Respiratory rate; 19.92 (1134)/min. , minute ventilation: 336.8? (93638) ml/kg, oxygen consumption; 7.95(410.22) ~nl/min/kg, arterial OZ capacity and saturation ; 18, 69 (13.523.0) vol. %and 82, 3 (6993.:i)%, heart rate; 183 (100250)/min, cardiac cut put; 200.13 (105396) ml/kg/min., mean arterial pressure; 155.5 (125190)mmHg, circulating blood volume; 87.79 (66.4119.1) ml/kg, number of red cells and white cells; 773.44 (5681000) X 10`´/mm3 and 14.55 (727) X 103/mm3, hematocrit; 45.36 (3162.8)%, ratio of arterial hematocrit versus venous hematocrit; 1: 0.98, iesectively.
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